Structural changes induced by osmotic water flow in rabbit proximal tubule
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چکیده
منابع مشابه
Developmental Changes in Rabbit Proximal Straight Tubule
The early proximal tubule preferentially reabsorbs organic solutes and bicarbonate over chloride ions resulting in a luminal fluid with a higher chloride concentration than that in blood. From this late proximal tubular fluid, half of NaCl reabsorption by the adult proximal tubule is active and transcellular and half is passive and paracellular. The purpose of the present in vitro microperfusio...
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Volume changes due to osmotic flow in the distal portion of proximal tubules of Necturi were measured by the split oil drop technique. In agreement with previous findings no volume flow was induced by NaCl concentrations close to 60 mM. The tubule wall was found to be permeable to plasma electrolytes, which have an apparent reflection coefficient of 0.69. The mean apparent hydraulic conductivit...
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The early proximal tubule preferentially reabsorbs organic solutes and bicarbonate over chloride ions, resulting in a luminal fluid with a higher chloride concentration than that in blood. From this late proximal tubular fluid, one-half of NaCl reabsorption by the adult proximal tubule is active and transcellular and one-half is passive and paracellular. The purpose of the present in vitro micr...
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This in vitro microperfusion study examined the effects of growth hormone and insulin-like growth factor I (IGF-I) on proximal convoluted tubule (PC1) transport. Tubules were perfused with an ultrafiltrate-like solution and bathed in a serumlike albumin solution. Neither a physiologic (5 X 10-10 M), nor a pharmacologic (5 X 10jM) dose of growth hormone had an effect on PCT phosphate or bicarbon...
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During normal kidney function, there are routinely wide swings in proximal tubule fluid flow and proportional changes in Na(+) reabsorption across tubule epithelial cells. This "glomerulotubular balance" occurs in the absence of any substantial change in cell volume, and is thus a challenge to coordinate luminal membrane solute entry with peritubular membrane solute exit. In this work, linear o...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1991
ISSN: 0085-2538
DOI: 10.1038/ki.1991.81